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Basic research

Protective Effect of Hydroxytyrosol Against Oxidative Stress Induced by the Ochratoxin in Kidney Cells.

Extra-Virgin Olive Oil and Intestinal Inflammation.

[Effects of benzo[a]pyrene subacute administrate on the cardiovascular of male Wistar rats].
Hydroxytyrosol and Oleuropein Inhibit Migration and Invasion via Induction of Autophagy in ER-Positive Breast Cancer Cell Lines (MCF7 and T47D).

A coupled enzymatic reaction of tyrosinase and glucose dehydrogenase for the production of hydroxytyrosol.

Cardiovascular disease

Pharmacokinetics of maslinic and oleanolic acids from olive oil - Effects on endothelial function in healthy adults.

Olive oil consumption and its repercussions on lipid metabolism.

Glucose metabolism

Mediterranean Diet Nutrients to Turn the Tide against Insulin Resistance and Related Diseases.

Health and lifestyle

Feasibility of the AusMed Diet Program: Translating the Mediterranean Diet for Older Australians.

Impact of an educational intervention on the quality of the Mediterranean diet, physical activity and weight status in adolescents.

Mental health

Adherence to a Mediterranean diet and cognitive function in the Age-Related Eye Disease Studies 1 & 2.


Traditional Dietary Patterns and Risk of Mortality in a Longitudinal Cohort of the Salus in Apulia Study.

Adherence to the Mediterranean Diet in Relation to All-Cause Mortality.

Neurodegenerative disease

Transcriptional response to a Mediterranean diet intervention exerts a modulatory effect on neuroinflammation signaling pathway.

Other topics

Participants with chronic pain do not perceive diet as a contributing factor to their pain.
Bioactives and health benefits of nuts and dried fruits.

Women health

A two-arm parallel double-blind randomised controlled pilot trial of the efficacy of Omega-3 polyunsaturated fatty acids for the treatment of women with endometriosis-associated pain (PurFECT1).

Other news

Mediterranean Diet Changes Gut Microbiome, Improves Health in Seniors


Multiple studies have shown an inverse association between good quality diet and onset or deterioration of mental diseases and cognitive function. This study in particular with 7,756 participants found protective associations attributed to vegetable and nut intakes. Additionally, participants who better adhered to the Mediterranean diet (MedDiet) showed lower risk of cognitive impairment and higher cognitive function scores. Among the components of the MedDiet, fish was the item with the most consistent evidence suggesting beneficial effect.
Related to cognitive function, an intervention conducted in high-cardiovascular risk patients assessed whether the MedDiet could exert beneficial effects on gene expression, specifically related to neuroinflammation, which is closely linked with the pathogenesis of neurodegenerative diseases. They observed that various signaling pathways associated with neuroinflammation were downregulated due to the modification of the dietary pattern, in this case a MedDiet enriched in either virgin olive oil or nuts. The explanation seems to be the presence of bioactive compounds and metabolites abundant in the MedDiet.
This recent meta-analysis analyzed the relationship between all-cause mortality and the adherence to the Mediterranean diet. Their conclusions were that all-cause mortality risk was associated with a 10% reduction for every 2-point increment in the MedDiet score. Foods such as fruits, vegetables, nuts and fish played a significant role, since they suggest being associated with factors of inflammation and oxidative stress.

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