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Basic research
(-)-Epigallocatechin-3-gallate and hydroxytyrosol improved antioxidative and anti-inflammatory responses in bovine mammary epithelial cells.

Cancer
Pre-diagnosis dietary pattern and survival in patients with multiple myeloma.

Cardiovascular disease
Association Between Lifestyle and Hypertriglyceridemic Waist Phenotype in the PREDIMED-Plus Study.
The effect of polyphenol-rich chardonnay seed supplements on peripheral endothelial function.
The association of dietary patterns and carotid intima-media thickness: A synthesis of current evidence.
Impact of different types of olive oil on cardiovascular risk factors: A systematic review and network meta-analysis.


Diabetes
High plasma glutamate and low glutamine-to-glutamate ratio are associated with type 2 diabetes: Case-cohort study within the PREDIMED trial.
Glycolysis/gluconeogenesis- and tricarboxylic acid cycle-related metabolites, Mediterranean diet, and type 2 diabetes.

Frailty
Diet quality and risk of frailty among older women in the Nurses' Health Study.

Gut microbiome
Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status

Health and lifestyle
The benefits of nutritional counselling for improving sport performance.
Weight Status, Adherence to the Mediterranean Diet, Physical Activity Level, and Sleep Behaviour of Italian Junior High School Adolescents.
Do healthy doctors deliver better messages of health promotion to their patients?: Data from the SUN cohort study.

Liver disease
The role of nutrition in non-alcoholic fatty liver disease: Pathophysiology and management.
Mental health
Association between the adherence to the Mediterranean dietary pattern and common mental disorders among community-dwelling elders
Purified oleocanthal and ligstroside protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing.
Dietary flavonols and risk of Alzheimer dementia.
DASH and Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND)

Metabolic syndrome
Mediterranean products as promising source of multi-target agents in the treatment of metabolic syndrome.

Obesity
Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome independently of energy intake.
Association between adherence to MIND diet and general and abdominal obesity: a cross-sectional study.

Other topics
Healthy Effects of Plant Polyphenols: Molecular Mechanisms.
Micronucleus Frequency in Exfoliated Buccal Cells of Children Living in an Industrialized Area of Apulia (Italy).
Association of Urinary Levels of Bisphenols A, F, and S with Endometriosis Risk: Preliminary Results of the EndEA Study.
Lifestyles and sexuality in men and women: the gender perspective in sexual medicine.
Factors Associated with Meat Consumption in Students of Spanish Universities: UniHcos Project.
Relationship between adherence to the Mediterranean Diet, intracerebral hemorrhage, and its location.
Vitamin D down-regulates the expression of some Th17 cell-related cytokines, key inflammatory chemokines, and chemokine receptors in experimental autoimmune encephalomyelitis.

Other news
Mediterranean Diet with EVOO decreases the need of antidiabetic drugs
https://www.oliveoiltimes.com/es/health-news/following-a-meddiet-with-evoo-lowers-need-for-medications-in-diabetics/69148
Top Quality Extra-Virgin Olive Oil Expo 20-22 March 2020
https://www.oliocapitale.it/en/

Summary:
Prevalence of hypertriglyceridemic waist (HTGW), which is characterized by abdominal obesity and high levels of triglycerides, was assessed among 6,732 participants of the PREDIMED-Plus study. Researchers concluded that those who smoked, had a sedentary lifestyle, higher BMI, and higher levels of glucose and lipid profile [total cholesterol, low density lipoproteins (LDL), and triglycerides (TG)] frequently had this HTGW phenotype. In contrast, those who followed the Mediterranean diet (MD) (abundant in olive oil), in most cases, did not show this phenotype. These results were independent of total energy intake.

Other study that included 82 subjects with high BMI, explored the effects of the MD on metabolic health and gut microbiome. Those subjects who better adhered to the MD reduced their plasma cholesterol and high-density lipoprotein, while increasing their gut microbiome diversity. Greater adherence also showed a reduction in systemic inflammation and possibly better glucose tolerance.

Moreover, a five-country European study related the gut microbiome with frailty, a condition that accompanies aging and carries an increased risk of poor health outcomes (falls, hospitalization, sarcopenia or chronic diseases among others). They concluded that a great gut microbioma diversity is positively associated with several markers of lower frailty and an improved cognitive function independently of the individual’s nationality.



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