|
|
|
|
|
Dear Colleagues and Friends,
|
- Interventional studies/RCTs
- Dietary patterns/Nutritional strategies
Over the past years, there has been increasing interest in describing the biological role of the various components in virgin olive oil (VOO) and their involvement in the pathophysiology of various chronic diseases. In this context, a recent review highlighted the biochemical perspective of phenolic and other bioactive compounds. As reported by the authors, there is scientific consensus and supporting evidence of the associations of VOO and health-related benefits. Yet, there is a need to further characterize the chemical structure of these and the remaining bioactive compounds in olive oil. Substantial epidemiological evidence was found on the associations between VOO and a lower incidence of chronic diseases; most of which involves oxidative damage. However, little evidence was found of metabolism and in vivo studies, lending to an incomplete understanding of the bioactivity and potential health benefits of VOO consumption.
|
|
There is no denying that most of the evidence of VOO consumption originates from studies on the health benefits of the Mediterranean diet (MedDiet) as it is one of the main components in this dietary pattern. In this context, a review from Salucci and colleagues highlighted the potential role of VOO in preventing loss of muscle mass leading upto sarcopenia, as a result of aging. The researchers highlight relevant biological pathways which involve EVOO and its bioactive compounds, and conclude in favor of the preventive potential of EVOO as a retardant of muscle loss and functional decline. According to this report, future research should include dietary supplementation of bioactive compounds or interventions with EVOO, as a sound nutritional approach to further understand its positive effects on aged-related muscle atrophy.
|
On the other hand, adherence to the MedDiet has been related to lower risk of type 2 diabetes (T2D) for its role on glycemic control, which has been partially attributed to the consumption of extra virgin olive oil (EVOO). For this reason, a group of researchers have explored the effects of EVOO on incretins (modulators of insulin release) as supportive T2D therapy and its preventive effects for general human health (next figure). This and similar reports, are the first steps to reformulate nutritional strategies for T2D therapy through an EVOO-enriched MedDiet.
|
|
|
|
|
|
|
|
|
