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Cognitive function and neurodegenerative diseases

Mediterranean diet during pregnancy and infant neurodevelopment: A prospective birth cohort study.

Longitudinal association between changes in resting-state network connectivity and cognition trajectories: The moderation role of a healthy diet.

The role of nutrition and the Mediterranean diet on the trajectories of cognitive decline.

Evaluating the association between the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet, mental health, and cardio-metabolic risk factors among individuals with obesity.

Association of Dietary Patterns with Parkinson's Disease: A Cross-Sectional Study Based on the United States National Health and Nutritional Examination Survey Database.

Mediterranean diet related metabolite profiles and cognitive performance.

Cardiovascular diseases and mortality

Circulating citric acid cycle metabolites and risk of cardiovascular disease in the PREDIMED study.

Better adherence to the MIND diet is associated with lower risk of all-cause death and cardiovascular death in patients with atherosclerotic cardiovascular disease or stroke: a cohort study from NHANES analysis.

Mediterranean Diet and its Effect on Endothelial Function: A Meta-analysis and Systematic Review.

Weight management

Association between adherence to the Mediterranean Diet and the Eatwell Guide and changes in weight and waist circumference in post-menopausal women in the UK Women's Cohort Study.

Weight management in young adults with type 1 diabetes: The advancing care for type 1 diabetes and obesity network sequential multiple assignment randomized trial pilot results.


Other diseases

Diet quality, food intake and incident adult-onset asthma: a Lifelines Cohort Study.

Mediterranean diet: a dietary pattern related to nutritional benefits for hemodialysis patients.

The Effect on Inflammation of Adherence to the Mediterranean Diet in Polycystic Ovary Syndrome.

Is Mediterranean diet associated with multiple sclerosis related symptoms and fatigue severity?

Mediterranean diet

Relationship between adherence to the Mediterranean diet, sustainable and healthy eating behaviors, and awareness of reducing the ecological footprint.

Other news

New research links olive oil consumption and reduce autoimmune diseases

Nutri-Score founder: olive oil will never attain the highest rating
News Briefs



Summary:

The worldwide burden of neurodegenerative diseases is enormous. In the absence of disease-modifying treatments, identifying modifiable risk factors over lifespan could alleviate the burden. Specifically, the Mediterranean Diet has been postulated as a potential alternative to prevent neurodegenerative diseases. In this sense, a prospective birth cohort study examined the effect of the Mediterranean diet (MedDiet) during pregnancy on infant neurodevelopment. The authors found that the MedDiet was inversely associated with communication domain developmental delays in infants. Interestingly, mediation analysis showed that such association could be partially mediated by C-peptide, but only among boys.
Another longitudinal study, conducted in adults aged 20-80 years, focused on the association between the MedDiet, brain structure and cognitive performance. On one hand, it analyzed the association of the MedDiet with changes in between- and within-network resting state functional connectivity (rsFC) - two neuroimaging measures of brain function- and with four cognitive tasks (memory, fluid reasoning, speed and attention, and vocabulary). The analyses showed no association between the MedDiet with within-network rsFC and any cognitive tasks, although the MedDiet was marginally associated with changes between-network rsFC. On the other hand, the authors evaluated the effect of the MedDiet on the association between rsFC and cognitive function. The results demonstrated that the MedDiet moderates the effect of change in between-network rsFC on change in memory domain.
The findings of both studies suggest that the MedDiet may protect cognitive function over the lifespan. Among other mechanisms that are widely explained in this narrative review, the gut-brain axis is postulated as a key mediator of the effect of nutrition on our brain health.

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