Another longitudinal study, conducted in adults aged 20-80 years, focused on the association between the MedDiet, brain structure and cognitive performance. On one hand, it analyzed the association of the MedDiet with changes in between- and within-network resting state functional connectivity (rsFC) - two neuroimaging measures of brain function- and with four cognitive tasks (memory, fluid reasoning, speed and attention, and vocabulary). The analyses showed no association between the MedDiet with within-network rsFC and any cognitive tasks, although the MedDiet was marginally associated with changes between-network rsFC. On the other hand, the authors evaluated the effect of the MedDiet on the association between rsFC and cognitive function. The results demonstrated that the MedDiet moderates the effect of change in between-network rsFC on change in memory domain.
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