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Dear Colleagues and Friends,
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Mediterranean Diet and components
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Obesity, Metabolic Syndrome
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The Mediterranean diet is considered a nutritional model with antioxidant and anti-inflammatory effects. In this regard, the inclusion of olive oil in this dietary pattern constitutes one of its main treasures. A recent study investigated the effects of dietary advanced glycation end products (dAGE), Mediterranean diet adherence screener (MEDAS) and oxidative balance score (OBS) on inflammation in people with type 2 diabetes. The researchers provided evidence on the association between dietary AGE intake and increased inflammation. Moreover, their results pointed out that both MEDAS & OBS have negative correlations with dAGE intake, suggesting their potential role in reducing inflammatory responses caused by high AGEs diets in persons suffering from T2D. Inflammation and oxidative stress are common mechanisms underlying many chronic diseases in which the Mediterranean diet can play an important protective role.
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Many of the Mediterranean diet’s beneficial effects are related to olive oil consumption. In this respect, another recent study focused on the health benefits and bioactivities associated with olive phenols. Researchers conducted experiments to determine if certain solid lipid nanoparticles could be used to improve the absorption rate of olive phenols in order to increase their biological benefits. The researchers used hydroxytyrosol oleate (HtyOle) and HtyOle-based solid lipid nanoparticles as the main components to achieve an increased bioavailability and a higher antioxidant activity. They were able to reduce reactive oxygen species (ROS) formation in cells, suggesting their potential use as an effective delivery system for olive phenolic compounds. This could lead to potentially greater health benefits associated with the consumption of olive oil, such as reducing risk factors for certain types of cancer and other diseases.
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