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Five U.S. Dietary Patterns and Their Relationship to Land Use, Water Use, and Greenhouse Gas Emissions: Implications for Future Food Security.

Exploring the Sustainable Benefits of Adherence to the Mediterranean Diet during the COVID-19 Pandemic in Italy.

Carbon dioxide (CO2) emissions and adherence to Mediterranean diet in an adult population: the Mediterranean diet index as a pollution level index.

Cognitive and mental health

Association between Psychological Disorders, Mediterranean Diet, and Chronotype in a Group of Italian Adults.

Nutrition Strategies Promoting Healthy Aging: From Improvement of Cardiovascular and Brain Health to Prevention of Age-Associated Diseases

MIND Dietary Pattern and Its Association with Cognition and Incident Dementia in the UK Biobank.

Mediterranean diet related metabolite profiles and cognitive performance.

Gastrointestinal disorders

The Mediterranean Diet in Paediatric Gastrointestinal Disorders.

Dietary adherence to the Mediterranean diet pattern in a randomized clinical trial of patients with quiescent ulcerative colitis.

Mediterranean Diet and Dietary Patterns

Circulating Amino Acids and Risk of Peripheral Artery Disease in the PREDIMED Trial.

Healthy Eating Patterns and Risk of Total and Cause-Specific Mortality.

Mediterranean Diet and Chronic Kidney Disease (CKD): A Practical Approach.

Dietary Patterns and Non-Communicable Disease Biomarkers: A Network Meta-Analysis and Nutritional Geometry Approach.


Lifestyle and Health-Related Quality of Life Relationships Concerning Metabolic Disease Phenotypes on the Nutrimdea Online Cohort.

Dietary and Physical Activity Habits as Conditioning Factors of Nutritional Status among Children of GENYAL Study.


Treatment of Dyslipidemia through Targeted Therapy of Gut Microbiota.

Oleic Acid

Update on Anti-Inflammatory Molecular Mechanisms Induced by Oleic Acid.

An antisteatosis response regulated by oleic acid through lipid droplet-mediated ERAD enhancement.

Other studies

Moderate Wine Consumption and Health: A Narrative Review.

Effectiveness of Goal-Directed and Outcome-Based Financial Incentives for Weight Loss in Primary Care Patients With Obesity Living in Socioeconomically Disadvantaged Neighborhoods: A Randomized Clinical Trial.

Effect of Oil Type Used in Neapolitan Pizza TSG Topping on Its Physical, Chemical, and Sensory Properties.


Olive oil, a characteristic component of the Mediterranean diet, has numerous positive effects on health, and convincing scientific literature indicates that it could play a key role in the health benefits of the Mediterranean diet, especially in cardiovascular health. In the PREDIMED trial, subjects following a Mediterranean diet supplemented with extra virgin olive oil were found to have a lower risk of peripheral arterial disease (PAD).

Moreover, adherence to the Mediterranean diet is associated with lower long-term risk of total and cause-specific mortality. A prospective cohort study of 2 large prospective cohorts (women from the Nurses’ Health Study (NHS; 1984-2020) and men from the Health Professionals Follow-up Study (HPFS; 1986-2020)) with up to 36 years of follow-up, provides additional information that supports this inverse relationship. In this study, the Alternate Mediterranean Diet (AMED) score was calculated to account for adherence to the Mediterranean diet. In both women and men, an inverse association was found between the AMED score and mortality caused by cardiovascular disease (CVD), cancer, respiratory disease and neurodegenerative disease in different racial and ethnic groups and other subgroups. A dose-dependent inverse association was observed between adherence to the Mediterranean diet and total mortality.

The main component of olive oil is oleic acid (OA) (70-80%), whose health benefits are mediated by an anti-inflammatory effect. However, the full mechanism by which oleic acid has beneficial effects is not yet known. This review updates our knowledge on the molecular mechanisms of OA. OA seems to influence cell membrane fluidity, receptors, signalling pathways and gene expression. It also regulates the synthesis and activity of antioxidant enzymes and activates sirtuin 1 (SIRT1). Some of the benefits of olive oil may be related to Oleoylethanolamide (OEA), which is derived from OA. OEA has anti-inflammatory and antioxidant effects and could be a potential therapeutic agent in the treatment of obesity, by regulating fat intake and energy homeostasis. However, most of the studies have been conducted in animals, hence more studies are needed to examine the properties of OA and OEA in humans.
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