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The unhealthy lifestyle in primary biliary cholangitis: An enemy to fight.

Adherence to a Mediterranean lifestyle improves metabolic status in coronary heart disease patients: A prospective analysis from the CORDIOPREV study.

Association between a Mediterranean lifestyle and growth differentiation factor 15: The seniors ENRICA-2 cohort.

Efficacy of an adjuvant non-face-to-face multimodal lifestyle modification program for patients with treatment-resistant major depression: A randomized controlled trial.

Mediterranean diet and dietary patterns

High adherence to the Mediterranean diet and Alternative Healthy Eating Index are associated with reduced odds of metabolic syndrome and its components in participants of the ORISCAV-LUX2 study.

Imbalanced dietary patterns, anthropometric, and body composition profiles amongst adults with Down syndrome.

Associations of healthy dietary patterns with mortality among people with prediabetes.


Lifestyle changes consist in modifying or implementing new habits to create a positive impact on our current and future health. Among those, the adoption of a healthy dietary pattern is of utmost importance and as abundant evidence has shown, the Mediterranean diet constitutes a stellar dietary option. The Mediterranean diet, which is based on a high consumption of extra virgin olive oil and plant-based foods that are rich in fibre and other phytonutrients, as well as a low intake of saturated fat, has consistently proved to be effective in mitigating the various cardiometabolic disorders that threaten the world today. This week’s articles focus mainly on cardiometabolic health and demonstrate how the adoption of the Mediterranean diet is associated with a better metabolic status in different populations.

The first article is from the CORDIOPREV study, an interventional study based on 1002 coronary heart disease patients, with a 5-year follow-up, that compared the effect of the Mediterranean diet vs a low-fat diet. It was demonstrated that a greater adherence to the Mediterranean Lifestyle could not only reduce the risk of metabolic syndrome, but also increase the probability of a metabolic syndrome reversal. These results echo those from the ORISCAV-LUX2 study, which also evidenced that high adherence to the Mediterranean diet, as well as other healthy eating guidelines, was associated with a reduced risk of metabolic syndrome in an adult population. Lastly, a national cohort study based on 8363 adults with prediabetes, found that the Mediterranean diet, alongside other healthy dietary patterns, was associated with an improved cardiometabolic profile and a lower risk of all-cause mortality.

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