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Cancer

BREAst Cancer Personalised NuTrition (BREACPNT): dietary intervention in breast cancer survivors treated with endocrine therapy - a protocol for a randomised clinical trial.

Dietary Inflammatory Index, Alternative Healthy Eating Index-2010, Mediterranean Diet Score and the risk of pancreatic cancer.



Cardiovascular Disease

Mediterranean Diet and its Effects on Silent Brain Infarcts in a Cohort of Patients With Atrial Fibrillation.

Nutritional recommendations in the prevention and treatment of atherogenic dyslipidemia.

Obesity, Metabolic syndrome

Adherence to the Mediterranean lifestyle pattern is associated with favorable weight loss outcomes: the MedWeight study.

Impact of Lifestyle Modification on Quality of Life in Patients with Metabolic Syndrome: Findings from the CHANGE Program Intervention Study in Prince Edward Island, Canada.

Other diseases

Effects of different dietary interventions in multiple sclerosis: a systematic review of evidence from 2018 to 2022.

Pregnancy

Maternal Mediterranean Diet Adherence and Its Associations with Maternal Prenatal Stressors and Child Growth.

Adults

Effectiveness of a multiple health-behaviour-change intervention in increasing adherence to the Mediterranean Diet in adults (EIRA study): a randomized controlled hybrid trial.

Effect of 30 days of ketogenic Mediterranean diet with phytoextracts on athletes' gut microbiome composition.

Children

Is adherence to the Mediterranean diet associated with good sleep duration in primary-school children?

Olive oil

Extra-virgin olive oil improves HDL lipid fraction but not HDL-mediated cholesterol efflux capacity: a double-blind, randomized, controlled, cross-over study (OLIVAUS).

Extra virgin olive oil extract rich in secoiridoids induces an anti-inflammatory profile in peripheral blood mononuclear cells from obese children.

Table olive elicits antihypertensive activity in spontaneously hypertensive rats.



Other studies

Comprehensive review of composition distribution and advances in profiling of phenolic compounds in oilseeds.

Is there an association between health literacy and adherence to the Mediterranean diet? A cross-sectional study in Greece.

Summary:

There is wide evidence of the health benefits of olive oil, especially for cardiovascular health and its risk factors. In this sense, a recent randomized, controlled, crossover trial studied the effect of olive oil on HDL cholesterol. The authors found that olive oil increases HDL cholesterol levels although no significant effect was found on the ability of this molecule to extract cholesterol from macrophages –also known as cholesterol efflux capacity– particularly in the blood vessel wall. In addition, a previous intervention study in rats suggests that table olives could reduce blood pressure regardless of body composition. During 7 weeks, table olives were administered to a model of spontaneously hypertensive rats and normotensive controls. After the intervention, hypertensive rats suffered a transient reduction in BP whereas no effect was found on normotensive rats. These results suggest that daily intake of olives could contribute to improving cardiovascular health through alternate mechanisms to body weight. On the other hand, inflammation is a concomitant status in cardiovascular disease and other chronic diseases.

Perhaps one of the best arguments to promote extra virgin olive oil (EVOO) arises from its ability to modulate chronic inflammation. Although the anti-inflammatory properties of EVOO have been demonstrated widely, the number of studies conducted in children has been limited. In response, an intervention trial studied the effect of EVOO on the modulation of the inflammatory response at the molecular level in peripheral blood mononuclear cells from obese children. The results demonstrated that EVOO reduced pro-inflammatory monocytes as well as the levels of chemokines involved in the recruitment of inflammatory cells. More and more studies continue to characterize the activity of olive oil on cardiometabolic health with great promise to aid standard care and prevent cardiovascular diseases.



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