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Mediterranean Diet and Physical Activity: Two Imperative Components in Breast Cancer Prevention.


Brain region specific disruption of mitochondrial bioenergetics in cynomolgus macaques fed a Western vs. a Mediterranean diet.

Mediterranean diet and cognitive function: From methodology to mechanisms of action.

Long-term diet quality and its change in relation to late-life subjective cognitive decline.

Maternal diet quality during pregnancy and child cognition and behavior in a US cohort.

MIND Diet and Cognitive Function over Eight Years in Puerto Rican Older Adults.

The Mediterranean Lifestyle and the Risk of Depression in Middle-Aged Adults.

Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) study: Rationale, design and baseline characteristics of a randomized control trial of the MIND diet on cognitive decline.


The Mediterranean diet and dietary approach to stop hypertension (DASH)-style diet are differently associated with lipid profile in a large sample of Iranian adults: a cross-sectional study of Shahedieh cohort.

Effects of a Calorie-Restricted Mediterranean-Style Diet on Plasma Lipids in Hypercholesterolemic South Korean Patients

Effect of extra virgin olive oil consumption on glycemic control: A systematic review and meta-analysis.

Influence of dietary patterns on the metabolically healthy obesity phenotype: A systematic review.

Weight Loss and Improvement of Metabolic Alterations in Overweight and Obese Children Through the I2AO2 Family Program: A Randomized Controlled Clinical Trial.
Dietary patterns and associations with biomarkers of inflammation in adults: a systematic review of observational studies.

Physical activity and metabolic syndrome severity among older adults at cardiovascular risk: 1-Year trends.

Benefits of Adding an Aquatic Resistance Interval Training to a Nutritional Education on Body Composition, Body Image Perception and Adherence to the Mediterranean Diet in Older Women.


Consumption of Enriched Yogurt with PAF Inhibitors from Olive Pomace Affects the Major Enzymes of PAF Metabolism: A Randomized, Double Blind, Three Arm Trial.

Three Healthy Eating Patterns and Cardiovascular Disease Risk Markers in 9 to 18 Year Olds With Body Mass Index >95%: A Randomized Trial.

Influence of the degree of adherence to the mediterranean diet and its components on cardiometabolic risk during pregnancy. The GESTAFIT project.


The effect of a Mediterranean diet vs. a low-fat diet on non-alcoholic fatty liver disease in children: a randomized trial.


Effects of Olive Oil on Striae Gravidarum in Primiparous Women: A Randomized Controlled Clinical.

Effect of the Mediterranean diet in patients with chronic spontaneous urticaria.


The effects of COVID-19 lockdown on lifestyle and emotional state in women undergoing assisted reproductive technology: Results of an Italian survey.


Metabolomic Biomarkers of Healthy Dietary Patterns and Cardiovascular Outcomes.
Interactions between caveolin 1 polymorphism and the Mediterranean and Mediterranean-DASH Intervention for Neurodegenerative Delay diet (MIND) diet on metabolic dyslipidemia in overweight and obese adult women: a cross-sectional study.


Application of the INFOGEST Standardized Method to Assess the Digestive Stability and Bioaccessibility of Phenolic Compounds from Galician Extra-Virgin Olive Oil.


Main drivers of (poly)phenol effects on human health: metabolite production and/or gut microbiota-associated metabotypes?

Global trends and performances of Mediterranean diet: A bibliometric analysis in CiteSpace.
Food Insecurity Among Older Adults: 10-Year National Trends and Associations with Diet Quality.

The impact of socioeconomic and environmental determinants on Mediterranean diet adherence: a municipal-level spatial analysis in Athens metropolitan area, Greece.

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Dyslipidemia is one of the main causes of cardiovascular disease and is a risk factor that can be modified through lifestyle improvements. This trend may be related to Western-style eating habits, characterized by excessive intake of unhealthy fats, sugar, animal protein, and low intake of fruits and vegetables. European guidelines (2016) indicate that appropriate dietary and lifestyle changes can prevent 80% of premature deaths from cardiovascular disease. Therefore, many countries recommend the Mediterranean diet as a therapeutic lifestyle modification.

A Korean randomized cross-over trial evaluated the short term effects of a calorie-restricted Korean style Mediterranean diet (KMD) versus a calorie-restricted conventional diet on the lipid profile and other metabolic parameters in hypercholesterolemic patients. Cardiometabolic parameters, including BMI, lipid profile, glycemic index, white blood cell count, fasting glucose, fasting insulin, and fatty liver index, improved in the calorie-restricted KMD intervention group after 4 weeks. The investigators concluded that a calorie-restricted Mediterranean diet not only help to treat dyslipidemia by improving the lipid parameters among individuals with hypercholesterolemia, but also reduces cardiovascular risk by improving chronic inflammation, hyperglycemia, and fatty liver disease.

Metabolomics, on the other hand, provide an opportunity to identify dietary biomarkers and better understand the molecular mechanisms underlying the associations between diet and cardiovascular disease. Results from one review suggest that a set of metabolites rather than a single metabolite, may be more appropriate for evaluating associations between diet-related metabolites and cardiovascular outcomes. Unsaturated lipids that reflect a higher consumption of fish and seafood, olive oil, or wine may represent an important pathway through which diet is associated with cardiovascular outcomes.

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