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OMICS

Mediterranean Diet and 12 months weight loss result in complex serum metabolomic and fecal metaproteomic changes in paediatric obesity

The Obesogenic Environment: Epigenetic Modifications in Placental Melanocortin 4 Receptor Gene Connected to Gestational Diabetes and Smoking.

Dietary patterns

Dietary Approaches and Health Outcomes: An Evidence Analysis Center Scoping Review.

Food and nutrient intake of school-aged children in Lebanon and their adherence to dietary guidelines and recommendations.

Technology-based nutrition interventions using the Mediterranean diet: a systematic review.

Neurocognitive

Associations Between Dietary Patterns and Neuroimaging Markers: A Systematic Review.

The Association Between Diet and Cardio-Metabolic Risk on Cognitive Performance: A Cross-Sectional Study of Middle-Aged Australian Adults.

​​Association of adherence to high-intensity physical activity and the Mediterranean-dietary approaches to stop hypertension intervention for neurodegenerative delay diet with cognition: A cross-sectional study.

Patterns of lifestyle behaviours from mid- through later-life in relation to exceptional episodic memory performance in older women: the Nurses' Health Study.

Fruit and Vegetable Dietary Patterns and Mental Health in Women: A Systematic Review.

Cardiovascular disease


Our Whole Lives for Hypertension and Cardiac Risk Factors-Combining a Teaching Kitchen Group Visit With a Web-Based Platform: Feasibility Trial.

Arginine catabolism metabolites and atrial fibrillation or heart failure risk: two case-control studies within the PREDIMED trial.

Dietary Acid Load but Not Mediterranean Diet Adherence Score Is Associated With Metabolic and Cardiovascular Health State: A Population Observational Study From Northern Italy.

Non-alcoholic fatty liver disease

Effect of a Six-Month Lifestyle Intervention on the Physical Activity and Fitness Status of Adults with NAFLD and Metabolic Syndrome.

Association between Stages of Hepatic Steatosis and Physical Activity Performance in Adults with Metabolic Syndrome: A Cross-Sectional Analysis in FLIPAN Study.

A Low Glycemic Index Mediterranean Diet Combined with Aerobic Physical Activity Rearranges the Gut Microbiota Signature in NAFLD Patients.

Obesity

Adherence to the Mediterranean Diet and Risk of Metabolically Unhealthy Obesity in Women: A Cross-Sectional Study.

Mediterranean Diet: What Are the Consequences for Menopause?

Other chronic disease

Alcohol, Drinking Pattern, and Chronic Disease.

Does Mediterranean Adequacy Index Correlate with Cardiovascular Events in Patients with Advanced Chronic Kidney Disease? An Exploratory Study.

Mediterranean Style Dietary Pattern with High Intensity Interval Training in Men with Prostate Cancer Treated with Androgen Deprivation Therapy: A Pilot Randomised Control Trial.

Association Between Lifestyle Changes, Mammographic Breast Density, and Breast Cancer.

Mediterranean diet and diabetes risk in a cohort study of individuals with prediabetes: propensity score analyses.

Others

Adherence to the Mediterranean diet and incident frailty: Results from a longitudinal study.

Food-Derived Bioactive Molecules from Mediterranean Diet: Nanotechnological Approaches and Waste Valorization as Strategies to Improve Human Wellness.

DIet and Health From reGIstered Trials on ClinicalTrials.gov: The DIGIT Study.

Major dietary patterns in relation to chronic low back pain; a cross-sectional study from RaNCD cohort.

Mediterranean-Type Diets as a Protective Factor for Asthma and Atopy.

Do Diet and Dietary Supplements Mitigate Clinical Outcomes in COVID-19?

Other news

The health Benefits of the olive oil

Summary

The Mediterranean diet is considered one of the healthiest dietary patterns to prevent diseases, in particular for the reduction of cardiovascular risk factors. Most recently its potential to prevent cognitive decline and neurodegeneration drew particular attention, especially after discovering the molecular mechanisms of how polyphenols, which are abundant in a fruit and vegetable rich MedDiet, alter brain structures. In their review Townsend et al. confirmed the impact of the MedDiet on neuronal health, visible in reduced brain atrophy over aging and protection against metabolic aberrations. Brain glucose metabolism is higher in people with high adherence to the MedDiet and therefore assures sufficient energy supply in neurons preventing onset of neurodegeneration. Besides, cerebral deposition of Aβ protein, an Alzheimer disease related biomarker, was found reduced. Many of these beneficial actions are linked to improved vasculature functioning involving healthy cerebral blood flow, reduced inflammation and oxidative stress. The authors highlight the connection between cardiovascular diseases and neurodegeneration as both share pathological changes in blood vessels as major factor in pathogenesis.
Further evidence for a neuro-beneficial effect was added by a case-control sample nested within the Nurses' Health Study (NHS) comparing women, between 80 and 87 years old, of exceptionally good episodic memory with participants showing average episodic memory function. An interesting finding was that adherence to MedDiet and physical activity at middle age (52-62 years) particularly stood out as predictors for later memory function. These findings point out first the importance to invigorate a healthy lifestyle including both sports and a high-quality diet and sIn econdly that prevention starts much earlier than disease onset. The association of Meddiet with memory functions confers credibility to the idea that the abovementioned Meddiet related mechanisms of neuroprotection influence clinical outcomes in the long run and sometimes with a certain lag phase as disease progression takes time.
The combination of physical activity and a healthy diet to prevent decline in cognition was further supported by a new cross-sectional analysis within the Health and Retirement Study. Adding the MIND diet, which is a dietary pattern close to the MedDiet with particular emphasis on intake of leafy greens and berries, to high-intensity physical activity was associated with higher global cognition when compared with high-intensity physical activity only. Unlike the above described findings of the NHS, these analyses imply a relevance of both lifestyle factors for prevention of neurodegeneration at advanced age, too.
In sum, the MedDiet deserves further promotion as it can slow down cognitive decline and the onset of neurodegenerative diseases. It appears that CVD and neurological diseases share common pathways, some of which are related to vascular pathologies. Therefore, the MedDiet, ideally combined with physical activity, offers a powerful preventive measure to address both public health challenges.
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