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Cardiovascular disease

A Remote Nutritional Intervention to Change the Dietary Habits of Patients Undergoing Ablation of Atrial Fibrillation: Randomized Controlled Trial

Remnant Cholesterol, Not LDL Cholesterol, Is Associated With Incident Cardiovascular Disease

Lipid Profiles and Heart Failure Risk: Results from Two Prospective Studies

Metabolic syndrome

Metabolic Syndrome Features and Excess Weight Were Inversely Associated with Nut Consumption after 1-Year Follow-Up in the PREDIMED-Plus Study

Bromatology

How olive washing and storage affect to fruit ethanol and virgin olive oil ethanol, ethyl esters and composition

Metabolites

Plasma Metabolomic Profiles of Glycemic Index, Glycemic Load, and Carbohydrate Quality Index in the PREDIMED Study

Dietary Patterns

Are dietary interventions with a behaviour change theoretical framework effective in changing dietary patterns? A systematic review

The effect of plant-based dietary patterns on blood pressure: a systematic review and meta-analysis of controlled intervention trials

Relationship between Dietary Patterns and Non-Alcoholic Fatty Liver Disease: a systematic review and meta-analysis

Mediterranean diet

The Mediating and Moderating Effects of Physical Fitness of the Relationship between Adherence to the Mediterranean Diet and Health-Related Quality of Life in University Students

Promoting health and preventing non-communicable diseases: evaluation of the adherence of the Italian population to the Mediterranean Diet by using the PREDIMED questionnaire

Association of the Modified Mediterranean Diet Score (mMDS) with Anthropometric and Biochemical Indices in US Career Firefighters

Updating the Mediterranean Diet Pyramid towards Sustainability: Focus on Environmental Concerns

The Effects of a Mediterranean Diet Intervention on Targeted Plasma Metabolic Biomarkers among US Firefighters: A Pilot Cluster-Randomized Trial

Obesity

Olive Leaf Extract, from Olea europaea L., Reduces Palmitate-Induced Inflammation via Regulation of Murine Macrophages Polarization

Meeting the Physical Activity Recommendations and Its Relationship with Obesity-Related Parameters, Physical Fitness, Screen Time, and Mediterranean Diet in Schoolchildren

Phenolic compounds

The challenge of exploiting polyphenols from olive leaves: addition to foods to improve their shelf-life and nutritional value

Determination of the Variability of Biophenols and Mineral Nutrients in Olive Leaves with Respect to Cultivar, Collection Period and Geographical Location for Their Targeted and Well-Timed Exploitation

Breast cancer

Adherence to the Mediterranean Diet and Mortality after Breast Cancer

Cognitive function

Dietary Habits and Risk of Early-Onset Dementia in an Italian Case-Control Study

Other news
Oil From Wild Olives Better at Lowering Blood Pressure, Researchers Find

7 medically-studied benefits of olive oil and why you should use it instead of butter




Summary:
In the Prevencion con Dieta Mediterranea (PREDIMED) trial, a primary prevention cohort of overweight and obese subjects at higher cardiovascular risk, baseline blood levels of triglycerides and remnant-cholesterol predicted adverse cardiovascular outcomes. This is especially noteworthy since these associations were not found for LDL-C, a well-established predictor of cardiovascular risk. This study expands our current knowledge on the atherogenicity of remnant-cholesterol and highlights the importance of this lipoprotein as a treatment target in this population. Another nested case-control study within the PREDIMED trial, with subsequent validation in a subsample of the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam cohort, evaluated the association of baseline targeted lipidomics profiles with the risk of developing heart failure. The need for effective preventive strategies is critical given this life-threatening disease affects millions worldwide. The authors specifically explored single lipids and network-based lipid clusters as risk factors for heart failure incidence. After confounder-adjustments, two lipid metabolites (ceramide 16:0 and phosphatidylcholine 32_0) and several lipidomic patterns were identified as putative biomarkers of heart failure risk. Given the scarce data on human lipid profile and heart failure, particularly as indicators of incident heart failure, their use as preclinical biomarkers is especially compelling.
The Mediterranean diet, rich in olive oil, nuts, fruits and vegetables, whole grains and pulses, fish, and limited in dairy products and red meat, has been repeatedly regarded as a healthy dietary pattern. While the evidence linking the Mediterranean diet with reduced all-cause mortality in the general population is broad, a new cohort of 1,453 women with breast cancer in northern Italy supports the beneficial role of pre-diagnostic Mediterranean diet adherence on the 15-year prognosis for these women. Both a reduction in both all-cause and breast cancer-specific mortality was observed, particularly among women over 55 years and overweight or obese.
Numerous studies evaluating the role of the Mediterranean diet on health outcomes have used a 14-item PREDIMED questionnaire to assess adherence to this dietary pattern in a simple manner. This questionnaire is less time-demanding, inexpensive, and requires less collaboration from participants than a typical full-length FFQ or similar methods. Researchers recently assessed adherence to the Mediterranean diet in an Italian population using this tool and highlighted its practicality for nutritional counselling in addition to a food frequency questionnaire or a food record. Another way to measure the Mediterranean Diet includes a previously validated modified Mediterranean Diet Score (mMDS). The “Feeding America’s Bravest” trial recently employed the mMDS in 60 fire stations in two Indiana (USA) fire departments. As expected, greater adherence to a Mediterranean diet was favorably associated with numerous anthropometric and biochemical parameters after adjustment by age and gender. Authors also identified changes in plasma metabolic biomarkers associated with a Mediterranean Diet intervention within a subsample of firefighters. The diet prompted changes in cardiovascular risk biomarkers, namely those related to lipid metabolism, including LDL-cholesterol, ApoB/ApoA1 ratio, remnant-cholesterol, M-VLDL-CE, and higher HDL-cholesterol, and better lipoprotein composition. Nonetheless, these changes were non-significant after correcting for multiple testing (except for a decrease in M-VLDL-CE).




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