The Mediterranean Diet (MedDiet), characterized by olive oil as one of its main components, is undeniably associated with numerous health benefits. However, the effects of the MedDiet on longevity are less well-known. A prospective cohort study in Southern Italy observed that a higher Mediterranean diet adherence has an important effect on lifespan. Strong negative effects were observed for individuals with medium to low adherence to this healthy dietary pattern, showing lower lifespans of 5.62% and 9.90%, respectively. Further research in other populations and geographic regions are needed to confirm these findings outside the Mediterranean basin area.